Nafamostat
Synonyms: Nafamostat mesylate, p-Guanidinobenzoic acid ester with 6-hydroxy-2-naphthamidine
Tags:
drug
small molecule
PubChem: 4413 4413 DrugBank: DB12598 DB12598 Related interactions
Related publications
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Homology Modeling of TMPRSS2 Yields Candidate Drugs That May Inhibit Entry of SARS-CoV-2 into Human Cells Stefano Rensi, Russ B Altman, Tianyun Liu, Yu-Chen Lo, Greg McInnes, Alex Derry, Allison Keys
Research
The anticoagulant nafamostat potently inhibits SARS-CoV-2 infection in vitro: an existing drug with multiple possible therapeutic effects Mizuki Yamamoto, Maki Kiso, Yuko Sakai-Tagawa, Kiyoko Iwatsuki-Horimoto, Masaki Imai, Makoto Takeda, Noriko Kinoshita, Norio Ohmagari, Jin Gohda, Kentaro Semba, Zene Matsuda, Yasushi Kawaguchi, Yoshihiro Kawaoka, Jun-ichiro Inou
Research
Treatments for COVID-19: emerging drugs against the coronavirus Francesco Potì, Cristina Pozzoli , Maristella Adami, Enzo Poli, Lucio G. Costa
Review
Comparative analysis of antiviral efficacy of FDA-approved drugs against SARS-CoV-2 in human lung cells: Nafamostat is the most potent antiviral drug candidate Meehyun Ko, Sangeun Jeon, Wang-Shick Ryu, Seungtaek Kim
Research
Accelerating drug development through repurposed FDA approved drugs for COVID-19: speed is important, not haste James T. Gordy, Kaushiki Mazumdar, Noton K. Dutta
Other
Spontaneous Binding of Potential COVID-19 Drugs to Human Serine Protease TMPRSS2 Zhu Haixia, Du Wenhao, Song Menghua, Liu Qing, Herrmann Andreas, Huang Qiang
Research
Structural insights into the binding modes of viral RNA-dependent RNA polymerases using a function-site interaction fingerprint method for RNA virus drug discovery Zheng Zhao, Phil Bourne
Research
Computational drug repurposing study of the RNA binding domain of SARS‐CoV‐2 nucleocapsid protein with antiviral agents Gizem Tatar, Ezgi Ozyurt, Kemal Turhan
Research
Supervised molecular dynamics for exploring the druggability of the SARS-CoV-2 spike protein Giuseppe Deganutti, Filippo Prischi, Christopher A. Reynolds
Research
Strong Binding of Leupeptin with TMPRSS2 Protease May Be an Alternative to Camostat and Nafamostat for SARS-CoV-2 Repurposed Drug: Evaluation from Molecular Docking and Molecular Dynamics Simulations Jaganathan Ramakrishnan, Saravanan Kandasamy, Ancy Iruthayaraj, Sivanandam Magudeeswaran, Kalaiarasi Chinnasamy, Kumaradhas Poomani
Research
A Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19 J. H. Shrimp, J. Janiszewski, C. Z. Chen, M. Xu, K. M. Wilson, S. C. Kales, P. E. Sanderson, P. Shinn, Z. Itkin, H. Guo, M. Shen, C. Klumpp-Thomas, S. G. Michael, W. Zheng, A. Simeonov, M. D. Hall,
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CORDITE (CORona Drug InTEractions database) collects and aggregates data from PubMed, MedRxiv, BioRxiv, ChemRxiv and PMC for SARS-CoV-2. Its main focus is set on drug interactions either addressing viral proteins or human proteins that could be used to treat COVID.
It collects and provides up-to-date information on computational predictions, in vitro, as well as in vivo study data.
The information provided is for research only and we cannot guarantee the correctness of the data.
Please contact dominik.heider@uni-muenster.de for further information.
Programmable access
There is an open API for access programmatically to the database. The API will print a JSON output:
Interactions
https://cordite-api.uni-muenster.de/api.php?action=list&table=interaction Targets
https://cordite-api.uni-muenster.de/api.php?action=list&table=target Drugs
https://cordite-api.uni-muenster.de/api.php?action=list&table=drug Publications
https://cordite-api.uni-muenster.de/api.php?action=list&table=publication Clinical trials
https://cordite-api.uni-muenster.de/api.php?action=list&table=clinical_trial
